I've used vacuum bleeders, pressure bleeders, gravity bleeding... even a long wooden rod to pump the pedal with while I worked the bleeder with the other hand...
NONE have seemed anywhere near as simple or effective as two dudes yelling at each other in a garage.
Seriously, after everything my favorite method is as follows:
One man in car, one man starting at furthest line.
Outside yells "PUMP" while pouring fluid into bottle, getting a wrench on the bleeder then running some hose from bleeder to fluid inside the bottle.
Inside yells "PUMPING" then pumps the brakes 4-5 times steadily
Inside then holds the pedal and yells "HOLD"
Outside cracks the bleeder and watches bubbles.
Inside waits for the pedal to hit the floor, then yells "FLOOR", while continuing to hold the pedal down.
Outside closes valve and yells "PUMP", and the cycle repeats, then onto next wheel.
It feels a bit foolish yelling back and forth constantly at first, but keeping track of where each other are and not having to guess makes things thoughtless and a lot quicker. We can bring a car in, get it on jack stands, bleed breaks and get it back out in just over 5 minutes.