I don't make big stuff based on my mill limitations imposed by my old basement shop stairs. The new place will fix all that...
Over the past 15 years I've ended up with a pretty full setup. A hotrodded Smithy 1340 Granite w/ Shooting Star DROs on 3 axis, loads of tooling, drill press, vertical and horizontal bandsaws, 12" disc/48" belt sander, shear, brake, notcher, TIG-MIG-gas welding, plasma cutter, bead blast, press, bench and pedestal grinders, tool grinder, 1" belt sander, and tons of smaller stuff.
I use all of it, all the time. I had a small side business making prototype lab instruments and doing performance mods on skateboard trucks for slalom and downhill racers. It paid for the the machine shop stuff and much of the fab stuff.
It's great being able to make anything you need, when you need it. It's saved the day for myself and any number of racer friends.
As my dad has always said "I can't imagine how you run a house without a lathe"