Ubuntu ftw!
Everything is very intuitive. Want a new program? Click Applications, Ubuntu Software Center, type in a description, and download. Don't want a program? Click Applications, Ubuntu Software Center, type in the name, and remove. Open Office is 100% compatible with Microsoft & Mac formats, and is free. Gimp is competitive with Photoshop, and is free. Really, almost everything is free.
You can download a disc image, burn it to a CD, and try it out before installing it. I did have trouble getting it to work on a Sony Vaio laptop, it used some weird GPU and none of the drivers would work. Everything else has been plug and play, from my cell phone, to the built in flash memory reader, to my USB wifi adapter.