2% less obese

Financial times article ozempic. 
https://archive.ph/2024.09.27-180929/https://www.ft.com/content/498c2c5e-fb9c-461e-8e9c-5429696b56a6

so

many people on these drugs that the whole country is 2% less obese.  This was recently called out by Walmart as a strategic headwind to their grocery revenue growth. 
 

it's wild to think that a drug has had this much of an impact in such a short time. I'm going to ignore the stupidity of normal people using it to be super thin. 

My sister in law is on it for diabetes, but she's lost a bunch of weight as a side effect. She needed to.

She's not necessarily healthier, though - no muscle tone and no cardio. My wife (her sister) probably outweighs her now, but is packing a whole bunch of muscle and has a cardiovascular system that's in much better shape. Losing weight is only part of getting healthy. But losing weight does make moving easier, so it's a good first step. 

To be clear, no one related to the source of the information has confirmed its related.to ozempic.

Im just wondering what the related side-effects will be 10-20 years down the road.  I forget if its ozempic, or just generic semaglutides, but there are already reports of increased risk of blindness associated with it

Keith Tanner said:

My sister in law is on it for diabetes, but she's lost a bunch of weight as a side effect. She needed to.

She's not necessarily healthier, though - no muscle tone and no cardio. My wife (her sister) probably outweighs her now, but is packing a whole bunch of muscle and has a cardiovascular system that's in much better shape. Losing weight is only part of getting healthy. But losing weight does make moving easier, so it's a good first step. 

  That is actually a really interesting discussion. A quick google shows inactivity increasing risk of all cause mortality by 38%, and type 2 diabetes increases the risk by 100%-200%. So stopping DM2 as quickly as possible is a really really important goal. It is going to be really interesting to see the long term effects and whether a medication can actually be a worthy antidote to our terrible food lifestyle.

Skinny fat is still fat.

Ya gotta move your body!

I'd rather be obese (I am) and do cardio for 3 or 5 hours week (mountain biking) than just have a great metabolism. 

I'm not sure the studies back that up, but I definitely seem to be healthier (even with my beer consumption) than those people that are naturally, or unnaturally skinny that don't move their bodies to the limit a few times a week.

I'm on a similar drug for my diabetes control. I have been decently active and not in perfect shape but still active and I feel not bad for almost 50. 

I was surprised, I went from 215 to high 190s (198 this morning) I was surprised with the weight loss TBH. I was not expecting to lose that much.

I don't think it's something that is sustainable as most I have seen are not making the lifestyle changes too. 

A combination of busting my ass, a complete rework of my diet, and a sister medication to ozempic (wegovy) saw me at 37%+ weight loss. The effects glp class medications have cannot be underestimated. 

In reply to wvumtnbkr :

I read an article in Scientific American about a condition called MHO Medically Healthy and Obese. This says that people with a high BMI are not necessarily unhealthy if all other indicators say they are ok. 

One of my personal truisms: the best drug is the one you don't have to take. 

DrMikeCSI said:

In reply to wvumtnbkr :

I read an article in Scientific American about a condition called MHO Medically Healthy and Obese. This says that people with a high BMI are not necessarily unhealthy if all other indicators say they are ok. 

Makes sense.  Look into the history of BMI.  It was originally calculated more via correlation than anything truly scientific. 

It has value, but mostly as a signpost.