A little late to the party, but I'll chime in.
First, gotta know tires and gears. GM automatics are pretty much interchangeable. Just make sure they come from a V8 or a 90 degree V6 (like the 4.3L). All Chevy bolt patterns will be the same up until the LS vehicles. Even those would bolt up, you'd just have an extra unused hole in the bellhousing.
Many GM vehicles will also be ready to accept any transmission that was offered from the factory. This gets hairy with trucks because there were frame differences between half ton and HD trucks, but it's pretty easy to check.
His truck probably came with a TH350. The easy button is... you guessed it, TH350. Starting somewhere around the late 70s or early 80s, GM did a TH350 with a lockup converter, sometimes called a TH350C. It is possible that frame combo also was available with a TH400, but they were never offered with a lockup converter. Both of those (with the exception of a kickdown and reverse light in some) are completely hydraulic and don't need wiring.
Quick rundown:
Metric trans family:
- THM200. Light duty 3-speed. Junk. Mostly used in intermediate cars like G-bodies when the most HP you could have was 140, and even then they didn't last long
- THM200-4r. Light duty 4-speed that is suprisingly not junk. Surviving big torque and abuse takes some careful parts choices. Narrow ratios and steep OD make it not a wise choice for a truck.
Non electric trans:
TH350. Standard fare 3-speed, narrow ratio, with or without lockup
TH400. HD 3-speed, narrow ratio, no lockup
700r4. basically a TH350 with OD and lockup. Wide ratio.
4L60. exactly the same as a 700r4, GM just changed how they name transmissions
Electric trans:
4L60E. As you would assume, a 700r4/4L60 that now needs a computer to operate
4L80E. This is more or less a TH400 with overdrive, but they never made a non-electric version. When they added the OD, they added a computer.
If it came with a TH350, the only direct bolt-ins would be a TH350. In a 2wd, the THM200-4r and THM200 would be direct bolt-ins, but as far as I know the metric trans were rarely offered with 4wd. TH400 will be a bolt-in if you have additional holes drilled for the crossmember and just get driveshafts from a TH400-equipped blazer.
You can probably also source a 700r4 and driveshafts from a later blazer (think like late 80s) if you go OD. Be aware that the 700r4 (and subsequent 4L60 and E) are a very wide ratio. This can be helpful for a heavy truck, but the 1-2 shift is the widest ratio drop of any automatic trans out there. Terrible performance choice, but often does well in trucks. OD is pretty tall at .70
With all of the above non-electric transmissions, you'll find that they employ any number of three connections for control:
-TV cable. Not a coax that delivers Nickelodeon signals, it is a physical cable from the throttle to a valve in the transmission
- Kickdown switch. This is a rotary switch and a 16 ga wire. The switch is usually under the dash on the accelerator lever, but sometimes on the carb.
- vacuum line to a modulator.
Any of those combinations can be easily added if you switch between families of transmission.